Synthesis of a 2,2'-bipyridyl functionalized oligovinylene-phenylene using Heck and Horner-Wadsworth-Emmons reactions and X-ray crystal structure of E-(4-(4-bromostyryl)phenyl)(methyl)sulfane.

نویسندگان

  • Orsolya Karácsony
  • Jeffrey R Deschamps
  • Scott A Trammell
  • Rafaela Nita
  • D Andrew Knight
چکیده

The synthesis of a new 2,2'-bipyridyl functionalized oligovinylenephenylene (OVP-5) containing a methyl protected thiol using Heck coupling and the Horner-Wadsworth-Emmons reaction and is described. A key step involving a diisopropylcarbodiimide promoted dehydration of a stable β-hydroxyphosphonate intermediate was identified. The structure of precursor E-(4-(4-bromostyryl)phenyl)(methyl)sulfane was determined using X-ray crystallography.

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عنوان ژورنال:
  • Molecules

دوره 17 5  شماره 

صفحات  -

تاریخ انتشار 2012